Blog

Disease Prevalence Effects on Dermatological AI Decisions

Author Image
The Centaur Blogging Team
February 2, 2022

Imagine that you are a dermatologist. You spend the morning seeing patients who have been referred to you for suspicion of skin cancer. Many of them do, in fact, have skin lesions that require treatment. We would say that disease "prevalence" was high in this set of patients.

Suppose that you next spend the afternoon giving annual screening exams to members of the general population. Here disease prevalence will be low. Would your morning’s work influence your decisions about patients in the afternoon?

In collaboration with Centaur Labs, Jeremy M. Wolfe, PhD, Professor of Ophthalmology & Radiology at Harvard Medical School, conducted a study published this month in Cognitive Research: Principles and Implications (CRPI) that tackled this question. We know from other contexts that recent history can influence current decisions, and we know that target prevalence has an impact on decisions.

In this study, Centaur Labs collected decisions about skin lesions from individuals with varying degrees of expertise using our proprietary medical imaging labeling app, DiagnosUs. Over 300,000 trials were collected in DiagnosUs over five days, with 803 participants in the study. This allowed the researcher to examine the effects of feedback history and prevalence in a single study.

This research finds that feedback educates observers, causing them to become more liberal when targets (diagnoses of melanoma) have been relatively common and more conservative when those targets are rare. The effects of a block of trials with feedback can last for days, with those effects showing up when the observer takes up a similar task again. It may be possible to use the educational effects of feedback when it is desirable to shift an observer's criterion, especially if the subsequent task does not involve reliable feedback.

Schedule a demo with Centaur.ai

Read the full study here:
Cognitive Research: Principles and Implications (CRPI)

Related posts

January 20, 2026

When AI Conversations Go Wrong and What High-Quality Data Can Do About It

A New York Times investigation shows how chatbot interactions can reinforce delusions and psychological harm. This response explains why the root cause is poor data quality and how Centaur.ai’s collective intelligence, performance-measured annotation, and superhuman datasets help teams build safer, more reliable high-stakes AI systems.

Continue reading →
January 11, 2023

Volastra Therapeutics Case Study | Chromosome Analysis

Worked with Volastra Therapeutics to annotate cancer cell images, supporting AI models in quantifying chromosomal instability and advancing cancer research.

Continue reading →
June 2, 2025

Multiple Opinions Drive Data Labeling Accuracy | Centaur AI

How Centaur.AI leverages multiple expert opinions to create the most accurate medical data labeling platform for text, image and video data

Continue reading →